NAHLS CORPORATION

Do you have such troubles?
New ingredients do not have such as...
  • safety data
  • New mechanism
  • Attractive history
  • Efficacy

if you do not solve these troubles, It may be difficult to use it, which prevents you to make new concept product. TOA KASEI CO.,LTD.

Which solutions would you choose for new?
Products
Choice history Efficacy Safety New Mechanism
1. Concept ingredient(Natural) ○ X X X
2. Existing ingredient with new data. △ ○ ○ △
3. Collaborated with Univ. ○ ○ ○ ○
The ingredient collaborated with University

The latest anti-aging Cosmetic Ingredient
developed by Kyoto Univ. and Osaka City Univ.


  • Manufacturer：NAHLS CORPORATION
  • Distributor：JTS CO.,LTD.
Application 1. Aqua-Collagen-Gel Enrich Lift EX
Product Description
  • Aqua-Collagen-Gel Enrich-Lift-EX is a superior "all-in-one gel" to cover eight-steps of skin treatment; Toner, Emulsion,BeautyEssence, Eye Treatment Cream, Facial Cream, Massage Cream, Facial Mask and Makeup Base. This ultimate moisturizer combats all signs of aging.

No1 sales in all-in-one gel for 4 years.

Active Ingredients :
  • WATER, GLYCERIN, DIGLYCERIN, SQUALANE, PENTYLENE GLYCOL, GLYCOSYL TREHALOSE, BUTYLENE GLYCOL, SOLUBLE COLLAGEN CROSSPOLYMER, SODIUM HYALURONATE CROSSPOLYMER, TETRADECYL AMINOBUTYROYLVALYLAMINOBUTYRIC UREA TRIFLUOROACETATE, PALMITOYL TRIPEPTIDE-5, PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINE, HYDROLYZED ELASTIN, SECALE CEREALE (RYE) SEED EXTRACT, GOLD, PLATINUM POWDER, HYDROLYZED COLLAGEN, HYDROLYZED HYALURONIC ACID, METHYL CARBOXYMETHYLPHENYL AMINOCARBOXYPROPYLPHOSPHONATE, PROCOLLAGEN, PASSIFLORA EDULIS FRUIT EXTRACT, CHLORELLA VULGARIS EXTRACT, GLYCINE SOJA (SOYBEAN) GERM EXTRACT, ROSA HYBRID FLOWER EXTRACT, PRUNUS MUME FRUIT EXTRACT, YEAST EXTRACT, HIBISCUS SYRIACUS CALLUS EXTRACT, THIOCTIC ACID, UBIQUINONE, RESVERATROL, SOY ISOFLAVONES, PUERARIA MIRIFICA ROOT EXTRACT, PUNICA GRANATUM EXTRACT, PUERARIA THUNBERGIANA ROOT EXTRACT, POLYGONUM CUSPIDATUM ROOT EXTRACT, CIMICIFUGA RACEMOSA ROOT EXTRACT, ANGELICA POLYMORPHA SINENSIS ROOT EXTRACT, TRIFOLIUM PRATENSE (CLOVER) FLOWER EXTRACT, SOLUBLE PROTEOGLYCAN, PLACENTAL PROTEIN, CUCUMIS MELO (MELON) PHYTOPLACENTA EXTRACT, HYDROLYZED MANGO JUICE EXTRACT, HYDROLYZED GARCINIA MANGOSTANA FRUIT EXTRACT, HYDROLYZED ANNONA CHERIMOLA FRUIT EXTRACT, PORPHYRIDIUM CRUENTUM EXTRACT, SODIUM CARBOXYMETHYL BETA-GLUCAN, NIACINAMIDE, SOLUBLE COLLAGEN, HYDROLYZED COLLAGEN PG-PROPYL METHYLSILANEDIOL, ISOSTEAROYL HYDROLYZED COLLAGEN, COLLAGEN, SODIUM HYALURONATE, HYDROXYPROPYLTRIMONIUM HYALURONATE, SODIUM ACETYLATED HYALURONATE, C12-13 ALKYL GLYCERYL HYDROLYZED HYALURONATE, CERAMIDE EOP, CERAMIDE NG, CERAMIDE NP, CERAMIDE AS, CERAMIDE AP, ELASTIN, DIPOTASSIUM GLYCYRRHIZATE, GLYCINE, SERINE, GLUTAMIC ACID, ASPARTIC ACID, LEUCINE, ALANINE, LYSINE, ARGININE, TYROSINE, PHENYLALANINE, THREONINE, PROLINE, VALINE, ISOLEUCINE, HISTIDINE, DIPALMITOYL HYDROXYPROLINE, PYRIDOXINE HCL, SODIUM RIBOFLAVIN PHOSPHATE, PELARGONIUM GRAVEOLENS OIL, LAVANDULA ANGUSTIFOLIA (LAVENDER) OIL, ORIGANUM MAJORANA LEAF OIL, CYMBOPOGON MARTINI OIL, MENTHA PIPERITA (PEPPERMINT) OIL, VETIVERIA ZIZANOIDES ROOT OIL, CITRUS AURANTIUM DULCIS (ORANGE) OIL, CUPRESSUS SEMPERVIRENS LEAF OIL, LIMNANTHES ALBA (MEADOWFOAM) SEED OIL, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, PHYTOSPHINGOSINE, HYDROGENATED STARCH HYDROLYSATE, TREHALOSE, 1,2-HEXANEDIOL, CAPRYLYL GLYCOL, ETHYLHEXYLGLYCERIN, PULLULAN, PVP, BETAINE, XANTHAN GUM, HYDROXYPROPYL METHYLCELLULOSE, CARBOMER, PHYTOSTERYL/OCTYLDODECYL LAUROYL GLUTAMATE, ISOSTEARIC ACID, CHOLESTEROL, GLYCINE SOJA (SOYBEAN) STEROLS, HYDROGENATED LECITHIN, SODIUM LAUROYL LACTYLATE, POTASSIUM HYDROXIDE, PENTASODIUM PENTETATE, CARAMEL, PHENOXYETHANOL
Application 2. Perfect Timeless
Product Description
  • The anti-aging care cream contains water-soluble fullerene*1 and oil-soluble fullerene*1 to provide firmness and radiance to the skin. In addition to that, 52 kinds of anti-aging care ingredients are distributed.
  • *1 FULLERENES (Skin conditioning ingredient) Introduce Kyoto University
Active Ingredients :
  • WATER, TRIETHYLHEXANOIN, GLYCERIN, BUTYLENE GLYCOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, BEHENYL ALCOHOL, PENTYLENE GLYCOL, HYDROGENATED RAPESEED ALCOHOL, STEARIC ACID, SORBITAN STEARATE, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, SQUALANE, GLYCERYL STEARATE SE, FULLERENES, GOLD, PLATINUM POWDER, SOLUBLE PROTEOGLYCAN, PLACENTAL PROTEIN, PUERARIA MIRIFICA ROOT EXTRACT, TRISODIUM ASCORBYL PALMITATE PHOSPHATE, UBIQUINONE, THIOCTIC ACID, CHRYSANTHELLUM INDICUM EXTRACT, ASPALATHUS LINEARIS EXTRACT, PINUS PINASTER BARK EXTRACT, HYDROXYRESVERATROL, SUPEROXIDE DISMUTASE, CAMELLIA JAPONICA SEED EXTRACT, BETULA ALBA BARK EXTRACT, ARTEMISIA PRINCEPS LEAF EXTRACT, GERANIUM THUNBERGII FLOWER/LEAF/STEM EXTRACT, SCUTELLARIA BAICALENSIS ROOT EXTRACT, ANGELICA KEISKEI LEAF/STEM EXTRACT, OLEA EUROPAEA (OLIVE) LEAF EXTRACT, VITIS VINIFERA (GRAPE) SEED EXTRACT, KINETIN, LACTOBACILLUS/BEAN SEED EXTRACT/SODIUM GLUTAMATE FERMENT FILTRATE, VACCINIUM MYRTILLUS LEAF EXTRACT, ROYAL JELLY EXTRACT, PALMITOYL TETRAPEPTIDE 7, PALMITOYL TRIPEPTIDE-1, ALPINIA SPECIOSA LEAF EXTRACT, RUBUS ELLIPTICUS ROOT EXTRACT, VERBENA OFFICINALIS EXTRACT, HEXAPEPTIDE-10, HYDROLYZED EGG SHELL MEMBRANE, ARBUTIN, OENOTHERA BIENNIS SEED EXTRACT, MALVA SYLVESTRIS (MALLOW) FLOWER/LEAF/STEM EXTRACT, MENTHA PIPERITA (PEPPERMINT) LEAF EXTRACT, PRIMULA VERIS EXTRACT, ALCHEMILLA VULGARIS EXTRACT, VERONICA OFFICINALIS FLOWER/LEAF/STEM EXTRACT, MELISSA OFFICINALIS LEAF EXTRACT, ACHILLEA MILLEFOLIUM EXTRACT, PUERARIA THUNBERGIANA ROOT EXTRACT, ALOE BARBADENSIS LEAF EXTRACT, CHLORELLA VULGARIS EXTRACT, PAEONIA ALBIFLORA ROOT EXTRACT, ASCOPHYLLUM NODOSUM EXTRACT, SAXIFRAGA SARMENTOSA EXTRACT, PELVETIA CANALICULATA EXTRACT, HYDROLYZED COLLAGEN, CERAMIDE NP, LAMINARIA OCHROLEUCA EXTRACT, METHYL CARBOXYMETHYLPHENYL AMINOCARBOXYPROPYLPHOSPHONATE, ERYTHRITOL, HOMARINE HCL, DIHYDROXYPROPYL ARGININE HCL, PRUNUS MUME FRUIT EXTRACT, ROSA HYBRID FLOWER EXTRACT, PLANTAGO MAJOR SEED EXTRACT, LACTOBACILLUS/PEAR JUICE FERMENT FILTRATE, LACTOBACILLUS/GRAPE JUICE FERMENT FILTRATE, TOCOPHEROL, ETHYLHEXYLGLYCERIN, DIMETHICONE, PHYTOSTERYL MACADAMIATE, PHYTOSTERYL/OCTYLDODECYL LAUROYL GLUTAMATE, ＰＶＰ, PULLULAN, CARBOMER, STEARETH-20, ARACHIDYL ALCOHOL, ARACHIDYL GLUCOSIDE, HYDROGENATED LECITHIN, GLYCINE SOJA (SOYBEAN) STEROLS, SODIUM HYDROXIDE, CYMBOPOGON MARTINI OIL, AMYRIS BALSAMIFERA BARK OIL, CANANGA ODORATA FLOWER OIL, FOENICULUM VULGARE (FENNEL) OIL, CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL, CORIANDRUM SATIVUM (CORIANDER）FRUIT OIL, JUNIPERUS COMMUNIS FRUIT OIL, PELARGONIUM GRAVEOLENS OIL, PHENOXYETHANOL
Application 3. QPRRY BU cream(NubraJapan)

Breast enlargement product with tensity and stiffness.

Active Ingredients :
  • WATER, ISOPENTYLDIOL, GLYCERIN, COCO-CAPRYLATE/CAPRATE, PUERARIA MIRIFICA ROOT EXTRACT, ANEMARRHENA ASPHODELOIDES ROOT EXTRACT, ACETYL HEXAPEPTIDE-38 , ALPHA-ARBUTIN, ASCORBYL TETRAISOPALMITATE, PANTHENOL, RETINYL PALMITATE, TOCOPHEROL, ARACHIS HYPOGAEA (PEANUT) OIL, SQUALANE, SODIUM HYALURONATE, HYDROXYPROPYLTRIMONIUM HYALURONATE, SOLUBLE COLLAGEN, HYDROLYZED COLLAGEN, METHYL CARBOXYMETHYLPHENYL AMINOCARBOXYPROPYLPHOSPHONATE, PELARGONIUM GRAVEOLENS FLOWER OIL, CANANGA ODORATA FLOWER OIL, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF OIL, CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, CARBOMER, XANTHAN GUM, POTASSIUM HYDROXIDE, HYDROGENATED POLYISOBUTENE, HYDROGENATED LECITHIN, SORBITOL, BUTYLENE GLYCOL, PHENOXYETHANOL
Application 4. All in one gel(Crystal Jemmy)

FAQ

Q1. Safety?
  • Japan Cosmetic Industry Association, a 9-item examination. ⇒ Toxicity, stimulativeness, side effects, etc. : not appeared.
  • Human monitor test(three months, 3 times) ⇒ Dry rough skin or a health problem: not appeared.
Q2. Is it expensive?
  • Yes, expensive, but recommended dosage is ca.0.005%(50ppm).
    We can sell it from 100g.
Q3. What is the attractive point for our marketing?
  • Nahlsgen® was developed by Kyoto University and Osaka City University.
Q4. How can Nahlsgen® penetrate into the skin?
  • Molecular weight is 331 and chemical structure is almost straight chain. it means it is easy to penetrate into the skin.
Q5. How about the compatibility?
  • Water soluble,
  • Insoluble ethanol, organic solvent
  • Stable in weak acid. Unstable in alkalii
Q6. Can I use Nahlsgen®'s name?
  • Yes, it is a registered-trademark.
Q7. What is the INCI name?
  • Display name date of approval: February, 2012
  • INCI name：Methyl CarboxymethylphenylAmino carboxypropylphosphonate
What is the new mechanism?
Mechanism detail
Skin structure and collagen production
Characteristic of Nahlsgen(for human cell)
For epidermal cell
  • Increase glutathione in epidermal cell.
  • Epidermal keratinocyte cell migration and promoting growing cell.
  • Enhance skin barrier function.
For fibroblast cell
  • collagen production
  • Elastin production
  • HSP47 production(Heat shock protein 47）
    • Protect cells under stress like aging and UV.
    • keep molecule of normal collagen and elastin.
    • Repair damededDNA and cells.
Function and effect of Nahlsgen
  • UV prevention, skin restoration
  • Improvement of skin elasticity
  • Increase in moisturizing effect
  • Maintenance of tension and gloss
  • Prevention of fine wrinkles
Work of Nahlsgen
Human monitor test
Characteristic of Nahlsgen
Chemical structure
Physico-chemical property
  • Molecular weight：３３１
  • Water soluble,Insoluble ethanol, organic solvent
  • Stable in weak acid. Unstable in alkalii
  • Recommended dosage ca.0.005% (50ppm)